The quality of evidence for medical interventions does not improve or worsen: a metaepidemiological study of Cochrane reviews

Архивировано 12.09.2020: howick-2020.pdf

Источник: Howick J., et al. The quality of evidence for medical interventions does not improve or worsen: a metaepidemiological study of Cochrane reviews. Journal of Clinical Epidemiology, 2020, DOI:10.1016/j.jclinepi.2020.08.005

Of the 608 reviews in the original sample, 154 had been updated with and 151 contained available data for both original and updated systematic reviews (24.8%). The updated reviews included: 15 (9.9%) with high-quality evidence, 56 (37.1%) with moderate-quality evidence, 47 (31.1%) with low-quality evidence, and 33 (21.9%) with very low-quality evidence. No change in the GRADE quality of evidence was found for most (103, 68.2%) of the updated reviews. The quality of evidence rating was downgraded in 28 reviews (58.3%) and upgraded in 20 (41.7%), although only six reviews were promoted to high quality.